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Italy in 2 Weeks

Rome to Amalfi — ancient ruins, Renaissance art, and coastal villages

2 weeks5 destinationsEUR 60–110/dayBest: Apr, May, Jun, Sep, Octeasy

This 14-day Italian circuit starts in Rome with four days of ancient history — the Colosseum, Vatican, and cobblestone piazzas. A high-speed train carries you north to Florence for Renaissance masterpieces and bistecca Fiorentina, then west to the colorful cliffside villages of Cinque Terre. Continue to Venice's labyrinthine canals before heading south to finish on the Amalfi Coast's sun-drenched terraces and limoncello-scented villages.

At a glance

Duration
2 weeks
Stops
5
Daily budget
EUR 60110
Total estimate
EUR 8401,540
Best months
Apr, May, Jun, Sep, Oct
Difficulty
easy

Estimates include lodging, food, local transport. Excludes flights.

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Stops on this route

1

Rome

Italy

4 days
  • Colosseum & Roman Forum
  • Vatican Museums & Sistine Chapel
  • Borghese Gallery
2

Florence

Italy

3 days
  • Uffizi Gallery
  • Brunelleschi's Cathedral Dome
  • Oltrarno & Piazzale Michelangelo
3

Cinque Terre

Italy

2 days
  • Vernazza village & harbor
  • Sentiero Azzurro coastal hiking trail
  • Manarola sunset viewpoint
4

Venice

Italy

2 days
  • St. Mark's Basilica & Campanile
  • Doge's Palace & Bridge of Sighs
  • Rialto Market & Grand Canal
5

Amalfi Coast

Italy

3 days
  • Positano's cliffside architecture
  • Path of the Gods (Sentiero degli Dei)
  • Ravello Villa Cimbrone Gardens

Day by Day

  1. 1

    Rome

    • Day 1

      Arrive in Rome — Colosseum & Trastevere

      Arrive at Fiumicino Airport and take the Leonardo Express to Roma Termini (30 minutes, 14 euros). Drop bags and head to the Colosseum — book combo tickets online with the Roman Forum and Palatine Hill (18 euros) and explore for 2-3 hours. Evening dinner in Trastevere: cacio e pepe at Da Enzo al 29 or supplì (fried rice balls) from a takeaway.

    • Day 2

      Vatican Museums, Sistine Chapel & St. Peter's

      Book Vatican Museums early admission (20 euros, 7 AM entry) to reach the Sistine Chapel before the crowds — Michelangelo's ceiling is overwhelming in the quiet morning light. Walk across St. Peter's Square to the basilica (free), climb the dome (8 euros) for panoramic city views, then explore Castel Sant'Angelo ramparts at golden hour.

    • Day 3

      Borghese Gallery, Piazza Navona & Campo de' Fiori

      Reserve the Borghese Gallery (13 euros, mandatory 2-hour time slot) for Bernini's Rape of Persephone and Apollo and Daphne — the finest baroque sculpture on earth. Walk to Piazza Navona for gelato at Giolitti, then to the Campo de' Fiori market for lunch. Evening: explore the Jewish Ghetto and eat artichokes alla giudia at Ba'Ghetto.

    • Day 4

      Pantheon, Trevi Fountain & Aperitivo Send-Off

      Morning at the Pantheon (free, best visited when it opens at 9 AM — the oculus beam of light moves across the marble floor as the sun climbs). Toss a coin in the Trevi Fountain and explore the Spanish Steps neighborhood. Have a final Roman aperitivo — Campari Spritz with olives and bruschetta — at a bar in the Prati neighborhood near the Vatican.

  2. 2

    Florence

    • Day 5

      Frecciarossa to Florence — Uffizi Gallery

      Transit

      Take the Frecciarossa high-speed train from Roma Termini to Florence Santa Maria Novella (90 minutes, from 19 euros booked in advance). Check into your accommodation and head to the Uffizi Gallery (20 euros — book at least a week ahead) to see Botticelli's Birth of Venus, Raphael's portraits, and Caravaggio's Medusa. Walk Ponte Vecchio at sunset.

    • Day 6

      Duomo, Accademia & Oltrarno Bistecca

      Climb Brunelleschi's Duomo dome (18 euros, timed entry at 8 AM opening) for terracotta rooftop views. Visit the nearby Accademia Gallery (12 euros) to stand before Michelangelo's original David — 5 meters of white marble up close is genuinely awe-inspiring. Evening: cross the Arno for dinner at Buca Mario or Buca dell'Orafo — try the bistecca Fiorentina (T-bone, sold per 100g).

    • Day 7

      Piazzale Michelangelo, San Miniato & Oltrarno

      Hike up to Piazzale Michelangelo at 7 AM for the finest panorama over Florence's dome-studded skyline, then walk up further to the green-and-white marble San Miniato al Monte church (free). Spend the afternoon exploring the Oltrarno artisan quarter — leather workshops, bookbinders, and frame-gilders line Via Maggio and Via de' Serragli. Aperitivo at Enoteca Pitti Gola.

  3. 3

    Cinque Terre

    • Day 8

      Train to Cinque Terre — Arrive in Vernazza

      Transit

      Take the train from Florence to La Spezia Centrale (2 hours, about 20 euros), then a local Trenitalia train to Vernazza (20 minutes). Check into a room with a sea view — book months ahead for peak season. Walk Vernazza's harbor promenade, swim off the rocks, and eat a plate of trofie al pesto (the local pasta shape) at Ristorante Belforte overlooking the sea.

    • Day 9

      Sentiero Azzurro Hike — All Five Villages

      Walk the Sentiero Azzurro (Cinque Terre Card, 7.50 euros/day for trains + trails) connecting Riomaggiore, Manarola, Corniglia, Vernazza, and Monterosso al Mare. The Manarola to Riomaggiore stretch (Via dell'Amore, recently reopened) takes 30 minutes; Vernazza to Monterosso takes 2 hours of steep coastal trail. Watch the Manarola sunset from the rocks above the harbor.

  4. 4

    Venice

    • Day 10

      Train to Venice — Grand Canal & Rialto

      Transit

      Take the Intercity or Frecciarossa from La Spezia to Venice Santa Lucia (3.5-4 hours, from 25 euros). Leave your bags at your hotel near Cannaregio or Castello (avoid hotels directly on the Grand Canal — they're 3x the price). Take vaporetto line 1 down the entire Grand Canal to learn the city's layout, then browse Rialto fish market (closed Sunday) and eat cicchetti (bar snacks) and Prosecco at Cantina Do Mori.

    • Day 11

      St. Mark's Basilica, Doge's Palace & Murano

      Visit St. Mark's Basilica at 9 AM (free, or pay 5 euros to skip the queue) — the Byzantine gold mosaics covering every ceiling are overwhelming. Book the Doge's Palace Secret Itinerary tour (28 euros) to walk the Bridge of Sighs and the hidden prisons. Afternoon: take the vaporetto to Murano island for free glassblowing demonstrations at the furnaces.

  5. 5

    Amalfi Coast

    • Day 12

      Travel to Amalfi Coast — Positano Arrival

      Transit

      Take a train from Venice Santa Lucia to Naples Centrale (4-5 hours with the Frecciarossa, from 30 euros), then a SITA bus or ferry from Naples to Positano (1.5-2 hours). Check into your accommodation in Positano — even budget rooms have terraces with sea views here. Walk the Church of Santa Maria Assunta with its majolica-tiled dome, swim at Spiaggia Grande, and eat pasta alle vongole overlooking the cliffside.

    • Day 13

      Path of the Gods & Amalfi Town

      Take the local SITA bus to Agerola and walk the Sentiero degli Dei (Path of the Gods) — a 7.5 km trail traversing the cliffs 600 meters above the sea with views of Capri and the Gulf of Salerno. Descend into Positano. Afternoon: take a 20-minute ferry to Amalfi town — visit the 9th-century Cathedral of Sant'Andrea and the cloistered Paradise Garden.

    • Day 14

      Ravello Gardens, Limoncello & Departure

      Transit

      Take a morning bus up to Ravello — visit Villa Cimbrone's Terrace of Infinity for what Gore Vidal called 'the most beautiful view in the world.' Buy a bottle of artisan limoncello from a family producer on Via Nazionale. Head back to Naples by ferry or bus for your departure train or flight home — Naples Centrale connects to Rome in 70 minutes by high-speed rail.

Related Itineraries

Further reading

Italy 2-Week Itinerary: Rome, Florence, Cinque Terre, Venice & Amalfi | TravelMaxing